Coating of Stents
Technology
The stents at DOT are coated with immunosuppressive drugs that possess an anti-proliferative effect and are applied homogenously using a carrier substance. The result is a so-called Drug Eluting Stent (DES). This DES releases small amounts of the drug over a defined time period, inhibits the formation of new cells and therefore reduces the risk of restenosis in this area. The coating process (combination of carrier substance and drug) is performed with a spraying process specially developed at DOT.
The stents at DOT are coated with immunosuppressive drugs that possess an anti-proliferative effect and are applied homogenously using a carrier substance. The result is a so-called Drug Eluting Stent (DES). This DES releases small amounts of the drug over a defined time period, inhibits the formation of new cells and therefore reduces the risk of restenosis in this area. The coating process (combination of carrier substance and drug) is performed with a spraying process specially developed at DOT.
Properties
- Homogenous, thin coating
- Defined release of drugs over a certain time period
Range of Application
- Stent angioplasty in blood vessels and coronary vessels, particularly for increased risk of restenosis
Advantages of the Procedure
- Effective inhibition of formation of new cells
- Permanent local effectiveness of released drugs over a longer time period